The most goals scored by a soccer/football shoe is the adidas F50. The shoe takes the number one spot in both the Premier League and the Primera Division. In the Primera Division the goals is over 200% of that scored by the second place Mercurial. The shoe comes in second in Serie A. However the shoe is absent from the top five in the Bundesliga, where the adidas Predator takes the number one spot.
I guess it makes sense beings that Lionel Messi wears them. Check out this post about the newly released Messi Special Edition F50’s.

Here’s a closer look at the shoe